The thalassemias are among the most common genetic disorders in the world. Individuals born with severe forms require clinical management that may include chronic transfusion therapy and regular iron chelation. Due to advances in treatment, individuals who are optimally managed are now living well beyond the age of 50. However, adult thalassemia patients are more likely to develop multiple disease-related morbidities. Adult patients may also develop conditions that are often encountered in the general aging population at an earlier age, which can create challenges for clinicians. In this Grand Rounds, Dr. Sayani will discuss the clinical management of thalassemia in patients over the age of 50. She will provide information on conditions and challenges that are more likely to occur in both the transfusion-dependent and non-transfusion-dependent populations, as well as treatment strategies for these individuals. A case study will be included.
Webinar on July 28th, 2025, from 2:00-3:00pm EST.
Register: https://register.gotowebinar.com/register/117512952906873176
Learning Objectives
1. List 3 complications frequently associated with transfusion-dependent thalassemia in older individuals.
2. List 3 complications frequently associated with non-transfusion-dependent thalassemia in older individuals.
3. Describe the recommended monitoring and treatment plan for thalassemia in individuals over 50.
These rounds are free and require advance registration. More information: cbutler@thalassemia.org
Presenter:
Farzana Sayani, MD, MSc, FRCPC
Site Lead, Red Cell Disorders Program University Health Network, Toronto
Moderator:
Scott A. Peslak, MD, PhD
Assistant Professor of Medicine
Director, Penn Comprehensive Adult Thalassemia Program
Division of Hematology/Oncology, University of Pennsylvania Perelman School of Medicine
